The genus Leea is a genus of medicinal plants. Half of this genus species are traditionally used to treat various ailments. This genus also holds promise for molecules that have the potential to be used as drugs or lead compounds in the discovery of a new drug. So far, 66 compounds have been isolated from this genus, 46 known to have pharmacological activity. Antioxidant, antimicrobial, anti-inflammatory and anticancer are the pharmacological activities most frequently found in these compounds. Although the toxicity studies are still limited to chronic toxicity tests showing low toxicity potential. The fact that various pharmacological activities and low potential make toxicity makes this plant worthy of continued study. The potential to possibility drugs from this genus is also huge.